Taken together, PS150 prevented stress-mediated reduction of serotonin and neurodegeneration in the rat brain and helped stressed rats achieved more normal behaviour demonstrating the psychotropic potential of PS150 via the gut-brain axis. Herein, the authors aim to evaluate the nisin effects on the apoptosis stimulation in the colon cancer cell line. The antimicrobial activity evaluation of biosurfactant against 6 human pathogenic microbes (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica Typhi, Listeria monocytogenes, and Candida albicans), demonstrated that biosurfactant produced by B. subtilis C19 have a specific antimicrobial activity. The pot experiment results indicated that SNAU02 rhamnolipid could be a promising agent in the biocontrol of Fusarium wilt of eggplant, which might help to minimize the yield loss of eggplant. Conclusively, isolates YK20, YK21, YK22 and YK32 were marked as promising biosurfactant producers and were subjected to identification. Effects of CO2 limitation on the metabolism of Pseudoclostridium thermosuccinogenes, In book: Microbial Diversity, Interventions and Scope (pp.259-299). <> The results showed a strong antimicrobial activity of the biosurfactant extract obtained from corn stream on pathogenic bacteria, in comparison with the L. pentosus biosurfactant extract. Here, our research presents the extracted biosurfactant’s anti-proliferative activity against lung cancer cells (A549), and anti-microbial and anti-biofilm activity against MRSA. However, recent advances in this field have enabled biocatalytic processes to compete head on with, and in some cases out perform, conventional chemical processing. endobj This is the first study dealing with the application of biosurfactant extracts on sensitive biological membranes, and this is the first time that the preservative capacity of a biosurfactant extract obtained in spontaneous fermentation is being evaluated, achieving promising results. Further, FT processes enhanced the total phenolic content (53–70%) and antioxidant activity by ORAC (69–102%) and FRAP (49–71%) assays of the soymilk matrix. 0000003545 00000 n The con cept of the book did not emanate from a meeting. This book is about biocatalysts and their past, present, and potential applications in the food, pharmaceutical, and chemical industries. The antimicrobial activity of RL against the Gram-positive pathogens L. monocytogenes, B. cereus and S. aureus was pH dependent and favored at more acidic conditions while the Gram-negative Salmonella enterica and E. coli (EHEC) showed resistance at all pH levels studied. Pharmacists and microbiologists work synergistically to ensure that drug therapies target the opportunistic microbes without harming its human host. 0000006666 00000 n Results: Yeast isolate, YK32, gave highest 8.4-cm oil displacement which was found to be significantly higher as compared to positive control, 0.2% (w/v) SDS (6.6 cm), followed by 6.2 and 6.0 cm by isolates YK20 and YK21, respectively. The biosurfactant from this marine yeast was purified and structurally characterized as Gal-Gal-Gal-Heptadecanoic acid (named as Cybersan) based on different spectral analysis. Consequently, it is utmost important On day 42, serum and brain tissue were collected 24 min after forced swim stress. Reproduce asexually via binary fission ! It could inhibit growth of C. albicans without inhibiting both gram-positive and gram-negative bacteria; therefore it could be promoted as antifungal active agent. Lactococcus lactis subsp. In this work, the lipopeptide biosurfactant produced by Indonesian marine bacteria, B. subtilis C19, was analyzed. Biosurfactant production appeared to be sensitive to varying pH as evident from the E24 index as high as 67.3% at pH 6.0 as compared with 60.2%, 60.1%, and 52.4% at pH 5.0, 5.5, and 7.0, respectively. The inhibition of biofilm was investigated by applying the toothpaste to biofilm formed in modified artificial saliva for 24 h at 37 °C in anaerobiosis. Here, we studied the effect of the available CO2 on the metabolism of Pseudoclostridium thermosuccinogenes, the only known succinate producing thermophile. Biosurfactants exhibited an efficient and successful application in various industries such as cosmetic, pharmaceutical, food, petroleum, agricultural, textile, and wastewater treatment. trailer optimistic for higher food production and to ensure future food availability in an The setup of this first textbook on biocatalysis is based on a professional reference book published in 1992, and it provides a basis for undergraduate and graduate courses in biocatalysis, as well as a condensed introduction into this field for scientists and professionals. CO2 limitation also prompted the formation of significant amounts of ethanol, which is only marginally produced during CO2 excess. Altogether, the changes in fermentation product yields result in increased ferredoxin and NAD+ reduction, and increased NADPH oxidation during CO2 limitation, which must be linked to reshuffled (trans) hydrogenation mechanisms of those cofactors, in order to keep them balanced. Conclusions: According to the action mechanism, AS-48 trypanocidal activity could be explained in a mitochondrion-dependent manner through a reactive oxygen species production and mitochondrial depolarization, causing a fast and severe bioenergetic collapse. An analysis of the scalability of the available technologies and the expected impact on process economics is presented, demonstrating the potential utility of integrated separation processes for bringing biosurfactants into mainstream commercialisation. Bacteriocins are generally produced by Gm+, Gm– and archaea bacteria. This bacteriocin also exhibited a wide range of antimicrobial activity against spoilage and pathogenic Gram-positive and Gram-negative bacteria. examination and expansion of novel anti-infective representatives, the use of microbes to perceive mutagenic and oncogenic prospective in medications and the usage of microbes in the production of insulin and various other human growth hormone. After the last corticosterone treatment, anxiety- and depression-like behaviors were tested within 4 days. The aim of this present study was to understand the antibacterial activity and mechanism of plantaricin LPL-1 against Listeria monocytogenes 54002, one of the Gram-positive bacteria sensitive to this bacteriocin and typical foodborne pathogenic bacteria in the food industry. 0 The diet also led to subtle but significant changes in the microbiota, with less abundant taxa being most affected. Rather, it is a compila tion of selected examples where biocatalysis either has already made a significant impact in the aforementioned industries, or has the potential to make a substantial contribution. PS150 reversed the decrease of serotonin, elevation of IDO and ameliorated brain degeneration in the rat brain induced by CMS. This article stresses on microbial fabricators and their potential to engender innovative biologically active compounds and their starring role in the simplification of human life. Maximum emulsification index was obtained in case of isolates YK20 and YK21 measuring 53.8%, after 6 days of incubation utilizing glucose as carbon source, whereas isolate YK32 was found to be reducing surface tension up to 93 dynes/cm and presented 99.6% degree of hydrophobicity. Bacteriocins, defined as ribosomally synthesized antimicrobial peptides, have traditionally been used as food preservatives, either added or produced by starter cultures during fermentation. © 2008-2020 ResearchGate GmbH. Yeast biomass yield equivalent to 10.3 g/L and 8.3 g/L was recorded at pH 6 and 7, respectively, during the production process. Strain FLU5 showed its capacity to produce biosurfactants from all tested substrates, in particular the residual frying oil, which is a cheap renewable carbon source alternative, thus minimizing the high cost of producing those surfactants. It could further decrease the surface tension of water from 72 to 31.4 ± 0.38 mN/m and was hence selected for subsequent study. 0000009382 00000 n The future of bacteriocins is largely dependent on getting FDA approval for use of other bacteriocins in addition to nisin to promote the research and applications.